Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib

Abstract Background/Aim Lenvatinib, a multikinase inhibitor, has become a second-line treatment option for unresectable liver cancer, while its monotherapy response rate is limited. Hence, we aim to investigate whether one of the epigenetic inhibitors will be synthetic lethal with Lenvatinib in live...

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Bibliographic Details
Main Authors: Yi Zong, Zhigang Tao, Siyi Jiang, Minyuan Wang, Weihua Yu
Format: Article
Language:English
Published: Springer 2024-03-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-024-00947-9