Differentiated mouse kidney tubuloids as a novel in vitro model to study collecting duct physiology

Differentiated mouse kidney tubuloids as a novel in vitro model to study collecting duct physiology

Kidney tubuloids are cell models that are derived from human or mouse renal epithelial cells and show high similarities with their in vivo counterparts. Tubuloids grow polarized in 3D, allow for long-term expansion, and represent multiple segments of the nephron, as shown by their gene expression pa...

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Bibliographic Details
Main Authors: C. J. A. Olde Hanhof, E. Dilmen, F. A. Yousef Yengej, F. Latta, C. M. E. Ammerlaan, J. Schreurs, L. Hooijmaijers, J. Jansen, M. B. Rookmaaker, I. Orhon, M. C. Verhaar, J. G. Hoenderop
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tubuloid
organoid
epithelial sodium transport
cell physiology
collecting duct
tubulopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1086823/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1086823/full

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