Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders

GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the central nervous system (CNS). Regulation of GABAAR trafficking and the control of their surface expression play important roles in the modulation of the strength of synaptic inhibition. Different pieces of evi...

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Bibliographic Details
Main Authors: Miranda Mele, Rui O. Costa, Carlos B. Duarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00077/full