PRDM16 regulates arterial development and vascular integrity

PRDM16 regulates arterial development and vascular integrity

Proper vascular formation is regulated by multiple signaling pathways. The vascular endothelial growth factor (VEGF) signaling promotes endothelial proliferation. Notch and its downstream targets act to lead endothelial cells toward an arterial fate through regulation of arterial gene expression. Ho...

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Bibliographic Details
Main Authors: Michael Thompson, Masahide Sakabe, Mark Verba, Jiukuan Hao, Stryder M. Meadows, Q. Richard Lu, Mei Xin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Physiology
Subjects:
PRDM16
vascular development
angiogenesis
angiopoietin
artery
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1165379/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1165379/full

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