Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability

Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability

Parvalbumin-expressing, fast spiking interneurons have high-energy demands, which make them particularly susceptible to energy impairment. Recent evidence suggests a link between mitochondrial dysfunction in fast spiking cortical interneurons and neuropsychiatric disorders. However, the effect of mi...

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Bibliographic Details
Main Authors: Melis Inan, Mingrui Zhao, Monica Manuszak, Cansu Karakaya, Anjali M. Rajadhyaksha, Virginia M. Pickel, Theodore H. Schwartz, Peter A. Goldstein, Giovanni Manfredi
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Neurobiology of Disease
Subjects:
COX
Interneurons
Mitochondria
Oscillations
Parvalbumin
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300778

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http://www.sciencedirect.com/science/article/pii/S0969996116300778

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