Mitochondrial Ca2+ remodeling is a prime factor in oncogenic behavior

Mitochondrial Ca2+ remodeling is a prime factor in oncogenic behavior

Cancer is sustained by defects in the mechanisms underlying cell proliferation, mitochondrial metabolism and cell death. Mitochondrial Ca2+ ions are central to all these processes, serving as signaling molecules with specific spatial localization, magnitude and temporal characteristics. Mutations in...

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Bibliographic Details
Main Authors: Alessandro eRimessi, Simone ePatergnani, Massimo eBonora, Mariusz R. Wieckowski, Paolo ePinton
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Autophagy
Calcium
Cell Death
Cancer
Ca2+ signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00143/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00143/full

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