Deciphering aging at three-dimensional genomic resolution

Aging is characterized by progressive functional declines at the organismal, organic, and cellular levels and increased susceptibility to aging-related diseases. Epigenetic alteration is a hallmark of aging, senescent cells show epigenomic changes at multiple scales, such as 3D genome reorganization...

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Bibliographic Details
Main Authors: Zunpeng Liu, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Cell Insight
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892722000311