Deciphering aging at three-dimensional genomic resolution
Aging is characterized by progressive functional declines at the organismal, organic, and cellular levels and increased susceptibility to aging-related diseases. Epigenetic alteration is a hallmark of aging, senescent cells show epigenomic changes at multiple scales, such as 3D genome reorganization...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | Cell Insight |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772892722000311 |