Protocolised early de-resuscitation in septic shock (REDUCE): protocol for a randomised controlled multicentre feasibility trial

Background Fluid overload is associated with excess mortality in septic shock. Current approaches to reduce fluid overload include restrictive administration of fluid or active removal of accumulated fluid. However, evidence on active fluid removal is scarce. The aim of this study is to assess the e...

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Bibliographic Details
Main Authors: David Berger, Alexa Hollinger, Martin Siegemund, Martin Müller, Carmen A Pfortmueller, Miodrag Filipovic, Joerg C Schefold, Anna Messmer, Urs Pietsch, Philipp Buehler, Jan Waskowski, Dominik E Uehlinger
Format: Article
Language:English
Published: BMJ Publishing Group 2023-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/9/e074847.full