An Integrated In Silico, In Vitro and Tumor Tissues Study Identified Selenoprotein S (SELENOS) and Valosin-Containing Protein (VCP/p97) as Novel Potential Associated Prognostic Biomarkers in Triple Negative Breast Cancer

An Integrated In Silico, In Vitro and Tumor Tissues Study Identified Selenoprotein S (SELENOS) and Valosin-Containing Protein (VCP/p97) as Novel Potential Associated Prognostic Biomarkers in Triple Negative Breast Cancer

Background. Triple negative breast cancer (TNBC) is a heterogeneous group of tumors with early relapse, poor overall survival, and lack of effective treatments. Hence, new prognostic biomarkers and therapeutic targets are needed. Methods. The expression profile of all twenty-five human selenoprotein...

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Bibliographic Details
Main Authors: Susan Costantini, Andrea Polo, Francesca Capone, Marina Accardo, Angela Sorice, Rita Lombardi, Palmina Bagnara, Federica Zito Marino, Martina Amato, Michele Orditura, Maddalena Fratelli, Gennaro Ciliberto, Alfredo Budillon
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
selenoproteins
biomarkers
SELENOS
VCP/p97
breast cancer
TNBC
Online Access:https://www.mdpi.com/2072-6694/14/3/646

Internet

https://www.mdpi.com/2072-6694/14/3/646

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