Screening neutral sites for metabolic engineering of methylotrophic yeast Ogataea polymorpha

Methylotrophic yeast Ogataea polymorpha is capable to utilize multiple carbon feedstocks especially methanol as sole carbon source and energy, making it an ideal host for bio-manufacturing. However, the lack of gene integration sites limits its systems metabolic engineering, in particular constructi...

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Bibliographic Details
Main Authors: Wei Yu, Jiaoqi Gao, Xiaoxin Zhai, Yongjin J. Zhou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-06-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X2100017X