Neuroprotection by the Immunomodulatory Drug Pomalidomide in the Drosophila LRRK2WD40 Genetic Model of Parkinson’s Disease

Neuroprotection by the Immunomodulatory Drug Pomalidomide in the Drosophila LRRK2WD40 Genetic Model of Parkinson’s Disease

The search for new disease-modifying drugs for Parkinson’s disease (PD) is a slow and highly expensive process, and the repurposing of drugs already approved for different medical indications is becoming a compelling alternative option for researchers. Genetic variables represent a predisposing fact...

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Bibliographic Details
Main Authors: Maria Antonietta Casu, Ignazia Mocci, Raffaella Isola, Augusta Pisanu, Laura Boi, Giovanna Mulas, Nigel H. Greig, Maria Dolores Setzu, Anna R. Carta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson
Drosophila
LRRK2
immunomodulation
neuroprotection
drug repurposing
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00031/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2020.00031/full

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