Profiling of plasma extracellular vesicles identifies proteins that strongly associate with patient’s global assessment of disease activity in rheumatoid arthritis

BackgroundRheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovial inflammation and cartilage/bone damage. Intercellular messengers such as IL-1 and TNF play a crucial role in the pathophysiology of RA but have limited diagnostic and prognostic values. Therefore, we asses...

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Bibliographic Details
Main Authors: Onno J. Arntz, Rogier M. Thurlings, Esmeralda N. Blaney Davidson, Pascal W. T. C. Jansen, Michiel Vermeulen, Marije I. Koenders, Peter M. van der Kraan, Fons A. J. van de Loo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1247778/full