Progressive brain rich-club network disruption from clinically isolated syndrome towards multiple sclerosis

Objective: To investigate the rich-club organization in clinically isolated syndrome (CIS) and multiple sclerosis (MS), and to characterize its relationships with physical disabilities and cognitive impairments. Methods: We constructed high-resolution white matter (WM) structural networks in 41 CIS,...

Full description

Bibliographic Details
Main Authors: Ni Shu, Yunyun Duan, Jing Huang, Zhuoqiong Ren, Zheng Liu, Huiqing Dong, Frederik Barkhof, Kuncheng Li, Yaou Liu
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218301049