Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles

Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles

Most viruses that replicate in the cytoplasm of host cells form neoorganelles that serve as sites of viral genome replication and particle assembly. These highly specialized structures concentrate viral proteins and nucleic acids, prevent the activation of cell-intrinsic defenses, and coordinate the...

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Bibliographic Details
Main Authors: Raquel Tenorio, Isabel Fernández de Castro, Jonathan J. Knowlton, Paula F. Zamora, Danica M. Sutherland, Cristina Risco, Terence S. Dermody
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
reovirus
rotavirus
bluetongue virus
double-stranded RNA
viral factories
viral inclusions
viral replication organelles
endoplasmic reticulum
viral nonstructural proteins
Online Access:https://www.mdpi.com/1999-4915/11/3/288

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https://www.mdpi.com/1999-4915/11/3/288

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