Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation

Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation

Objectives: Epidemiological studies indicate that first- and second-hand cigarette smoke (CS) exposure are important risk factors for the development of type 2 diabetes (T2D). Additionally, elevated diabetes risk has been reported to occur within a short period of time after smoking cessation, and h...

Full description

Bibliographic Details
Main Authors: Xin Tong, Zunaira Chaudhry, Chih-Chun Lee, Robert N. Bone, Sukrati Kanojia, Judith Maddatu, Paul Sohn, Staci A. Weaver, Morgan A. Robertson, Irina Petrache, Carmella Evans-Molina, Tatsuyoshi Kono
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Molecular Metabolism
Subjects:
Ceramide
Smoking
Insulin secretion
Oxidative stress
β-cell
Type 2 diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782030048X

Internet

http://www.sciencedirect.com/science/article/pii/S221287782030048X

Similar Items