DEVELOPMENT OF ORAL NIFEDIPINE-LOADED POLYMERIC NANOCAPSULES: PHYSICOCHEMICAL CHARACTERISATION, PHOTOSTABILITY STUDIES, <italic>IN VITRO</italic> AND <italic>IN VIVO</italic> EVALUATION

DEVELOPMENT OF ORAL NIFEDIPINE-LOADED POLYMERIC NANOCAPSULES: PHYSICOCHEMICAL CHARACTERISATION, PHOTOSTABILITY STUDIES, <italic>IN VITRO</italic> AND <italic>IN VIVO</italic> EVALUATION

<p>In this study, nifedipine (NFP)-loaded polymeric nanocapsules were prepared and characterised with a view to protect the drug from degradation. Nanocapsule suspensions were prepared using two different surfactants (pluronic F68 and polyvinyl alcohol). Physicochemical stability and <itali...

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Bibliographic Details
Main Authors: Monika Piazzon Tagliari, Andrea Granada, Marcos Antonio Segatto Silva, Hellen Karine Stulzer, Betina Giehl Zanetti-Ramos, Daniel Fernandes, Izabella Thais Silva, Claudia Maria Oliveira Simões, Regina Sordi, Jamil Assreuy, Valdir Soldi
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2015-07-01
Series:Química Nova
Subjects:
nifedipine
nanocapsule
polymeric material
stability
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000600781&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000600781&lng=en&tlng=en

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