Engineered <i>Lactobacillus paracasei</i> Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice

Engineered <i>Lactobacillus paracasei</i> Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice

Palmitoylethanolamide (PEA) is an <i>N</i>-acylethanolamide produced on-demand by the enzyme <i>N</i>-acylphosphatidylethanolamine-preferring phospholipase D (NAPE-PLD). Being a key member of the larger family of bioactive autacoid local injury antagonist amides (ALIAmides),...

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Bibliographic Details
Main Authors: Giuseppe Esposito, Marcella Pesce, Luisa Seguella, Jie Lu, Chiara Corpetti, Alessandro Del Re, Fatima Domenica Elisa De Palma, Giovanni Esposito, Walter Sanseverino, Giovanni Sarnelli
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
palmitoylethanolamide
ulcerative colitis
probiotic
<i>Lactobacillus paracasei</i>
pharmacotherapy
Online Access:https://www.mdpi.com/1422-0067/22/6/2945

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https://www.mdpi.com/1422-0067/22/6/2945

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