Progressive APOBEC3B mRNA expression in distant breast cancer metastases.

Progressive APOBEC3B mRNA expression in distant breast cancer metastases.

BACKGROUND:APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expres...

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Bibliographic Details
Main Authors: Anieta M Sieuwerts, Willemijne A M E Schrijver, Simone U Dalm, Vanja de Weerd, Cathy B Moelans, Natalie Ter Hoeve, Paul J van Diest, John W M Martens, Carolien H M van Deurzen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5283735?pdf=render

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http://europepmc.org/articles/PMC5283735?pdf=render

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