Thermodynamic Overview of Bioconjugation Reactions Pertinent to Lysine and Cysteine Peptide and Protein Residues

Thermodynamic Overview of Bioconjugation Reactions Pertinent to Lysine and Cysteine Peptide and Protein Residues

Bioconjugation reactions are critical to the modification of peptides and proteins, permitting the introduction of biophysical probes onto proteins as well as drugs for use in antibody-targeted medicines. A diverse set of chemical reagents can be employed in these circumstances to covalently label p...

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Bibliographic Details
Main Authors: Maja Lopandic, Fatima Merza, John F. Honek
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Compounds
Subjects:
chemical modification
bioconjugation
protein modification
density functional theory
computation
thermodynamics
Online Access:https://www.mdpi.com/2673-6918/3/3/35

Internet

https://www.mdpi.com/2673-6918/3/3/35

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