Optimizing animal models of autoimmune encephalitis using active immunization

Optimizing animal models of autoimmune encephalitis using active immunization

Background and objectivesEncephalitis is a devastating neurologic disorder with high morbidity and mortality. Autoimmune causes are roughly as common as infectious ones. N-methyl-D-aspartic acid receptor (NMDAR) encephalitis (NMDARE), characterized by serum and/or spinal fluid NMDAR antibodies, is t...

Full description

Bibliographic Details
Main Authors: Jenny Linnoila, Negin Jalali Motlagh, Grace Jachimiec, Chih-Chung Jerry Lin, Enrico Küllenberg, Gregory Wojtkiewicz, Rudolph Tanzi, John W. Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
autoimmune encephalitis
NMDA receptor encephalitis
mouse model
active immunization
experimental autoimmune encephalomyelitis (EAE)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177672/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1177672/full

Similar Items