OX1 and OX2 orexin/hypocretin receptor pharmacogenetics
Orexin/hypocretin peptide mutations are rare in humans. Even though human narcolepsy is associated with orexin deficiency, this is only extremely rarely due to mutations in the gene coding prepro-orexin, the precursor for both orexin peptides. In contrast, coding and non-coding variants of the OX1 a...
| Auteurs principaux: | , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Frontiers Media S.A.
2014-05-01
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| Collection: | Frontiers in Neuroscience |
| Sujets: | |
| Accès en ligne: | http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00057/full |