Proteomics Profiling with SWATH-MS Quantitative Analysis of Changes in the Human Brain with HIV Infection Reveals a Differential Impact on the Frontal and Temporal Lobes

Proteomics Profiling with SWATH-MS Quantitative Analysis of Changes in the Human Brain with HIV Infection Reveals a Differential Impact on the Frontal and Temporal Lobes

The chronic irreversible regression of cognitive ability and memory function in human immunodeficiency virus (HIV)-associated dementia (HAND) is linked with late-stage HIV infection in the brain. The molecular-level signatures of neuroinflammation and neurodegeneration are linked with dysfunction in...

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Bibliographic Details
Main Authors: Mayur Doke, Tamizhselvi Ramasamy, Vaishnavi Sundar, Jay P. McLaughlin, Thangavel Samikkannu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Brain Sciences
Subjects:
proteomics
SWATH
HIV-associated dementia
frontal lobe
human brain
LC-MS/MS
Online Access:https://www.mdpi.com/2076-3425/11/11/1438

Internet

https://www.mdpi.com/2076-3425/11/11/1438

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