Overcoming off-target optical stimulation-evoked cortical activity in the mouse brain in vivo

Summary: Exogenous opsins allow for in vivo interrogation of brain circuits at unprecedented temporal and spatial precision. Here, we found that optical fiber laser stimulation at wavelengths of 637, 594, or 473 nm within the cortex of mice lacking expression of exogenous opsins resulted in a strong...

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Bibliographic Details
Main Authors: Simon Weiler, Mateo Velez-Fort, Troy W. Margrie
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224023770