Celecoxib/Cyclodextrin Eye Drop Microsuspensions: Evaluation of In Vitro Cytotoxicity and Anti-VEGF Efficacy for Retinal Diseases

Celecoxib/Cyclodextrin Eye Drop Microsuspensions: Evaluation of In Vitro Cytotoxicity and Anti-VEGF Efficacy for Retinal Diseases

Celecoxib (CCB), a cyclooxygenase-2 inhibitor, is capable of reducing oxidative stress and vascular endothelial growth factor (VEGF) expression in retinal cells and has been shown to be effective in the treatment of diabetic retinopathy and age-related macular degeneration. However, the ocular bioav...

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Bibliographic Details
Main Authors: Phatsawee Jansook, Hay Man Saung Hnin Soe, Rathapon Asasutjarit, Theingi Tun, Hay Marn Hnin, Phyo Darli Maw, Tanapong Watchararot, Thorsteinn Loftsson
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
cyclodextrin
celecoxib
eye drop
microsuspensions
cytotoxicity
anti-VEGF
Online Access:https://www.mdpi.com/1999-4923/15/12/2689

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https://www.mdpi.com/1999-4923/15/12/2689

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