Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus.

Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus.

BACKGROUND:Normal-pressure hydrocephalus (NPH) is a neurodegenerative disorder that usually occurs late in adult life. Clinically, the cardinal features include gait disturbances, urinary incontinence, and cognitive decline. METHODOLOGY/PRINCIPAL FINDINGS:Herein we report the characterization of a n...

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Main Authors: Ming-Jen Lee, Ching-Pang Chang, Yi-Hsin Lee, Yi-Chih Wu, Hsu-Wen Tseng, Yu-Ying Tung, Min-Tzu Wu, Yen-Hui Chen, Lu-Ting Kuo, Dennis Stephenson, Shuen-Iu Hung, Jer-Yuarn Wu, Chen Chang, Yuan-Tsong Chen, Yijuang Chern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2774278?pdf=render

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http://europepmc.org/articles/PMC2774278?pdf=render

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