p16: cycling off the beaten path

p16: cycling off the beaten path

p16INK4A (hereafter called p16) is a faithful cellular ally in the fight against tumorigenesis. Although its canonical pathway through retinoblastoma (RB) is well delineated, RB-independent functions for p16 are beginning to emerge. Here we summarize non-canonical roles of p16, including our recent...

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Bibliographic Details
Main Authors: Raquel Buj, Katherine M. Aird
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Molecular & Cellular Oncology
Subjects:
retinoblastoma
cell cycle
senescence
nucleotide metabolism
mtorc1
reactive oxygen species
nf-κb
jnk1/3
sp1
ap-1
Online Access:http://dx.doi.org/10.1080/23723556.2019.1677140

Internet

http://dx.doi.org/10.1080/23723556.2019.1677140

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