Male germ cell apoptosis and epigenetic histone modification induced by Tripterygium wilfordii Hook F.

Multiglycosides of Tripterygium wilfordii Hook f (GTW), a Chinese herb-derived medicine used as a remedy for rheumatoid arthritis, are considered to be a reversible anti-fertility drug affecting the mammalian spermatids. However, the mechanism behind this effect is still unknown. To study the possib...

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Bibliographic Details
Main Authors: Ji Xiong, Hu Wang, Guangming Guo, Shuzeng Wang, Liqun He, Haifeng Chen, Ji Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3115959?pdf=render