Matrix metalloproteinase-7 is increased in lung bases but not apices in idiopathic pulmonary fibrosis

Matrix metalloproteinase-7 is increased in lung bases but not apices in idiopathic pulmonary fibrosis

Introduction Idiopathic pulmonary fibrosis (IPF) is a progressively fibrotic lung condition with poor prognosis. Matrix metalloproteinase-7 (MMP7) is a protein secreted by epithelial cells in IPF lungs. It is not known if MMP7 expression correlates with fibrotic changes in lung tissue. Methods Tissu...

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Bibliographic Details
Main Authors: Jade Jaffar, Mae Wong, Gregory A. Fishbein, Monther Alhamdoosh, Laura McMillan, Cristina Gamell-Fulla, Milica Ng, Nick Wilson, Karen Symons, Ian Glaspole, Glen Westall
Format: Article
Language:English
Published: European Respiratory Society 2022-10-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/8/4/00191-2022.full

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http://openres.ersjournals.com/content/8/4/00191-2022.full

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