Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan <i>Oxyuranus scutellatus</i> Venoms

Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan <i>Oxyuranus scutellatus</i> Venoms

Antivenom is currently the standard-of-care treatment for snakebite envenoming, but its efficacy is limited by treatment delays, availability, and in many cases, species specificity. Many of the rapidly lethal effects of envenoming are caused by venom-derived toxins, such as phospholipase A2 (sPLA2)...

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Bibliographic Details
Main Authors: Lyndi L. Gilliam, John Gilliam, Stephen P. Samuel, Rebecca W. Carter, Jerry Ritchey, Tommaso Bulfone, José María Gutiérrez, David J. Williams, Daniela M. Durkin, Sally I. Stephens, Matthew R. Lewin
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Toxins
Subjects:
snakebite
<i>Oxyuranus</i>
coastal taipan
venom
antivenom
phospholipase A2 inhibitors
Online Access:https://www.mdpi.com/2072-6651/15/9/557

Internet

https://www.mdpi.com/2072-6651/15/9/557

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