Obese locus in WNIN/obese rat maps on chromosome 5 upstream of leptin receptor.

WNIN/Obese (WNIN/Ob) rat a new mutant model of metabolic syndrome was identified in 1996 from an inbred Wistar rat strain, WNIN. So far several papers are published on this model highlighting its physical, biochemical and metabolic traits. WNIN/Ob is leptin resistant with unaltered leptin or its rec...

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Bibliographic Details
Main Authors: Rajender Rao Kalashikam, Kiran Kumar Battula, Veerababu Kirlampalli, Jeffrey M Friedman, Giridharan Nappanveettil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804619?pdf=render