Patterns of chromosome abnormalities in a sample of Colombian patients with chronic myeloid leukemia

Patterns of chromosome abnormalities in a sample of Colombian patients with chronic myeloid leukemia

Chronic Myeloid Leukemia (CML) is characterized by the presence of the Philadelphia (Ph) chromosome, resulting from a translocation between chromosomes 9 and 22 that gives rise to the BCR-ABL1 fusion gene. The Ph chromosome is present in 95 % of CML cases. In 5 %-10 % of these cases Ph variants oc...

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Bibliographic Details
Main Authors: Azucena Largo-Peralta, Milena Rondón-Lagos, Diana Sánchez-Peñarete, Katherin Cordón, Cladelis Rubio, Maribel Forero-Castro
Format: Article
Language:English
Published: Pontificia Universidad Javeriana 2023-12-01
Series:Universitas Scientiarum
Subjects:
leukemia; neoplasm; chromosome aberrations; philadelphia chromosome; trisomy; fluorescence in situ hybridization; reverse transcriptase polymerase chain reaction.
Online Access:https://revistas.javeriana.edu.co/index.php/scientarium/article/view/37540

Internet

https://revistas.javeriana.edu.co/index.php/scientarium/article/view/37540

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