Hypoxia induced exosomal Circ-ZNF609 promotes pre-metastatic niche formation and cancer progression via miR-150-5p/VEGFA and HuR/ZO-1 axes in esophageal squamous cell carcinoma

Hypoxia induced exosomal Circ-ZNF609 promotes pre-metastatic niche formation and cancer progression via miR-150-5p/VEGFA and HuR/ZO-1 axes in esophageal squamous cell carcinoma

Abstract Exosomes derived from cancer are regarded as significant mediators of cancer-host crosstalk. Hypoxia, on the other hand, is one of the essential characteristics of solid tumors. This research set out to discover how circulating exosomes from hypoxic esophageal squamous cell carcinoma (ESCC)...

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Bibliographic Details
Main Authors: Yu Mao, Jiahao Wang, Yimin Wang, Zhanzhao Fu, Lixin Dong, Jia Liu
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01905-8

Internet

https://doi.org/10.1038/s41420-024-01905-8

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