Characterizing Lipid‐Coated Mesoporous Silica Nanoparticles as CD169‐Binding Delivery System for Rilpivirine and Cabotegravir

Characterizing Lipid‐Coated Mesoporous Silica Nanoparticles as CD169‐Binding Delivery System for Rilpivirine and Cabotegravir

Herein, lipid‐coated mesoporous silica nanoparticles (LMSNs) are investigated as biomimetic delivery vehicle for two antiretroviral (ARV) compounds, rilpivirine (RPV), and cabotegravir (CAB). Monosialodihexosylganglioside (GM3) is incorporated into the membrane to facilitate LMSN binding to CD169 (S...

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Bibliographic Details
Main Authors: Han Zang, Josiane Fofana, Fangda Xu, Sarah B. Nodder, Suryaram Gummuluru, Björn M. Reinhard
Format: Article
Language:English
Published: Wiley-VCH 2022-05-01
Series:Advanced NanoBiomed Research
Subjects:
antiretroviral drugs
drug delivery
lipid-coated mesoporous silica nanoparticles
Online Access:https://doi.org/10.1002/anbr.202100157

Internet

https://doi.org/10.1002/anbr.202100157

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