Design and rationale for the WARFA trial: a randomized controlled cross-over trial testing the therapeutic equivalence of branded and generic warfarin in atrial fibrillation patients in Brazil

Design and rationale for the WARFA trial: a randomized controlled cross-over trial testing the therapeutic equivalence of branded and generic warfarin in atrial fibrillation patients in Brazil

Abstract Background Warfarin is a commonly used anticoagulant. Whether a given dose of the different formulations of Brazilian warfarin will result in the same effect on the international normalized ratio (INR) is uncertain. The aim of the WARFA trial is to determine whether the branded and two gene...

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Bibliographic Details
Main Authors: Carolina Gomes Freitas, Michael Walsh, Álvaro Nagib Atallah
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Warfarin
Generic drug
Generic drugs
Brazil
Statistical analysis plan
Crossover
Online Access:http://link.springer.com/article/10.1186/s12872-017-0584-4

Internet

http://link.springer.com/article/10.1186/s12872-017-0584-4

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