Production of Plant-Derived Japanese Encephalitis Virus Multi-Epitope Peptide in <i>Nicotiana benthamiana</i> and Immunological Response in Mice

Production of Plant-Derived Japanese Encephalitis Virus Multi-Epitope Peptide in <i>Nicotiana benthamiana</i> and Immunological Response in Mice

The current production of the Japanese encephalitis virus (JEV) vaccine is based on animal cells, where various risk factors for human health should be resolved. This study used a transient expression system to express the chimeric protein composed of antigenic epitopes from the JEV envelope (E) pro...

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Bibliographic Details
Main Authors: Jae-Wan Jung, Pil-Gu Park, Won-Kyung Lee, Jun-Hye Shin, Mi-Hwa Jang, Eun-Hye Seo, Timothy An, Young Beom Kim, Myeong Hee Moon, Seuk-Keun Choi, Jee Sun Yun, Kee-Jong Hong, Seong-Ryong Kim
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
Japanese encephalitis virus (JEV)
multi-epitope peptide (MEP)
recombinant protein
transient expression
<i>Nicotiana benthamiana</i>
Online Access:https://www.mdpi.com/1422-0067/24/14/11643

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https://www.mdpi.com/1422-0067/24/14/11643

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