Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies

Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies

We report that, labeling mouse muscle tissue, with mouse monoclonal antibodies specific to slow or fast myosin heavy chain (sMyHC and fMyHC, respectively), can lead to artefactual labeling of damaged muscle fibers, as hybrid fibers (sMyHC+ and fMyHC+). We demonstrate that such erroneous immunopheno...

書誌詳細
主要な著者:	Morium Begam, Joseph A. Roche
フォーマット:	論文
言語:	English
出版事項:	PAGEPress Publications 2018-07-01
シリーズ:	European Journal of Histochemistry
主題:	Skeletal muscle myosin heavy chains fiber type immunolabeling hybrid muscle fibers muscle fiber damage
オンライン･アクセス:	https://ejh.it/index.php/ejh/article/view/2896

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