Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa

Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa

Curbing PD-1 immunosuppressive signaling represents an effective immune awakening or immune-reactivation approach for tumor eradication for many cancers. Yet, the potential involvement of this critical PD-1 immunosuppressive signaling in de novo malignant transformation of epithelial cells to pre-ca...

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Bibliographic Details
Main Authors: Yichen Chen, Qiusheng Li, Xinye Li, Da Ma, Juan Fang, Liqun Luo, Xiangqi Liu, Xi Wang, Vivian Wai Yan Lui, Juan Xia, Bin Cheng, Zhi Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:OncoImmunology
Subjects:
immunotherapy
programmed death receptor 1
pre-cancerous lesions
squamous cell carcinomas
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1388484

Internet

http://dx.doi.org/10.1080/2162402X.2017.1388484

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