Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

Abstract Background Despite early interest in the health effects of polyunsaturated fatty acids (PUFA), there is still substantial controversy and uncertainty on the evidence linking PUFA to cardiovascular diseases (CVDs). We investigated the effect of plasma concentration of omega-3 PUFA (i.e. doco...

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Bibliographic Details
Main Authors: Maria Carolina Borges, Philip C. Haycock, Jie Zheng, Gibran Hemani, Michael V. Holmes, George Davey Smith, Aroon D. Hingorani, Deborah A. Lawlor
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Medicine
Subjects:
Fatty acids
Cardiovascular diseases
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-022-02399-w

Internet

https://doi.org/10.1186/s12916-022-02399-w

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