Lymphangiogenesis and angiogenesis rescue murine ischemic hindlimb via transient receptor potential vanilloid 4

In this study, we assessed the regulation of transient receptor potential vanilloid 4 (TRPV4) promoting lymphangio/angiogenesis to improve the ischemic hindlimb animal model, and revealed that (1) a TRPV4 agonist improved the blood flow of ischemic hindlimbs by inducing both angiogenesis and lymphan...

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Bibliographic Details
Main Authors: Hideaki Yamada, Naoaki Sakata, Tomoko Tanaka, Hideaki Tagashira, Gumpei Yoshimatsu, Ryo Kawakami, Hideichi Wada, Takahiro Iwamoto, Shohta Kodama
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000426