Cohesin-Mediated Chromatin Interactions and Autoimmunity

Cohesin-Mediated Chromatin Interactions and Autoimmunity

Proper physiological functioning of any cell type requires ordered chromatin organization. In this context, cohesin complex performs important functions preventing premature separation of sister chromatids after DNA replication. In partnership with CCCTC-binding factor, it ensures insulator activity...

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Bibliographic Details
Main Authors: Venkataragavan Chandrasekaran, Nina Oparina, Maria-Jose Garcia-Bonete, Caroline Wasén, Malin C. Erlandsson, Eric Malmhäll-Bah, Karin M. E. Andersson, Maja Jensen, Sofia T. Silfverswärd, Gergely Katona, Maria I. Bokarewa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
cohesin
CCCTC-binding factor
autoimmunity
genome organization
immune signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.840002/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.840002/full

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