Solid Lipid Nanoparticles as Carriers for the Synthetic Opioid LP2: Characterization and In Vitro Release

Solid Lipid Nanoparticles as Carriers for the Synthetic Opioid LP2: Characterization and In Vitro Release

A synthetic dual-target mu opioid peptide receptor/delta opioid peptide receptor anti-nociceptive ligand, named LP2, has emerged as a promising candidate for the management of acute and/or persistent pain, but its lipophilicity limits further developments as a therapeutic agent. In this work, to all...

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Bibliographic Details
Main Authors: Angelo Spadaro, Lorella Pasquinucci, Miriam Lorenti, Ludovica Maria Santagati, Maria Grazia Sarpietro, Rita Turnaturi, Carmela Parenti, Lucia Montenegro
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Applied Sciences
Subjects:
solid lipid nanoparticles
diastereoisomers
LP2
multitarget ligand
opioids
anti-nociceptive agents
Online Access:https://www.mdpi.com/2076-3417/11/21/10250

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https://www.mdpi.com/2076-3417/11/21/10250

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