Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway

Wolfram syndrome 1b mutation suppresses Mauthner-cell axon regeneration via ER stress signal pathway

Abstract Wolfram Syndrome (WS) is a fatal human inherited disease with symptoms of diabetes, vision decreasing, and neurodegeneration caused by mutations in the endoplasmic reticulum (ER)-resident protein WFS1. WFS1 has been reported to play an important role in glucose metabolism. However, the role...

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Bibliographic Details
Main Authors: Zongyi Wang, Xinliang Wang, Lingyu Shi, Yuan Cai, Bing Hu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Acta Neuropathologica Communications
Subjects:
wfs1b
Zebrafish
Mauthner cell
ER stress
Regeneration
Online Access:https://doi.org/10.1186/s40478-022-01484-8

Internet

https://doi.org/10.1186/s40478-022-01484-8

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