Clustered Regularly Interspaced Short Palindromic Repeat-Dependent, Biofilm-Specific Death of <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Mediated by Increased Expression of Phage-Related Genes

ABSTRACT The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (CRISPR/Cas) system is an adaptive immune system present in many archaea and bacteria. CRISPR/Cas systems are incredibly diverse, and there is increasing evidence of CRISPR/Cas systems playing a role in...

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Bibliographic Details
Main Authors: Gary E. Heussler, Kyle C. Cady, Katja Koeppen, Sabin Bhuju, Bruce A. Stanton, George A. O’Toole
Format: Article
Language:English
Published: American Society for Microbiology 2015-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00129-15