Ozone induces autophagy by activating PPARγ/mTOR in rat chondrocytes treated with IL-1β

Abstract Background Osteoarthritis (OA) is the main cause of older pain and disability. Intra-articular injections of ozone (O3) commonly have been found to have antioxidative and anti-inflammatory effects to reduce pain and improve function in knee osteoarthritis. It has been reported that reduced...

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Bibliographic Details
Main Authors: Panpan Sun, Weicheng Xu, Xu Zhao, Cong Zhang, Xiaowen Lin, Moxuan Gong, Zhijian Fu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03233-y