Integrative population pharmacokinetic/pharmacodynamic analysis of nemonoxacin capsule in Chinese patients with community-acquired pneumonia

Integrative population pharmacokinetic/pharmacodynamic analysis of nemonoxacin capsule in Chinese patients with community-acquired pneumonia

Introduction: Nemonoxacin is an innovative quinolone antibiotic for treatment of community-acquired pneumonia (CAP). As more data are available from clinical studies, it is necessary to perform an integrative pharmacokinetic/pharmacodynamic (PK/PD) analysis to support and justify the optimal dosing...

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Bibliographic Details
Main Authors: Yuancheng Chen, Xiaojie Wu, Chengyuan Tsai, Liwen Chang, Jicheng Yu, Guoying Cao, Beining Guo, Yaoguo Shi, Demei Zhu, Fupin Hu, Jinyi Yuan, Yang Liu, Xu Zhao, Yingyuan Zhang, Jufang Wu, Jing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
nemonoxacin
community-acquired pneumonia
population pharmacokinetics
pharmacokinetic/pharmacodynamic analysis
Streptococcus pneumoniae
Klebsiella pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.912962/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.912962/full

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