Two-Step Purification of L-Asparaginase from Acrylaway® L

Two-Step Purification of L-Asparaginase from Acrylaway® L

Abstract L-Asparaginase (L-ASNase) is a biopharmaceutical used for acute lymphoblastic leukaemia (ALL) treatment, dramatically increasing the patients’ chance of cure. However, its production and distribution in developing countries were disrupted because of its low profitability, which caused great...

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Bibliographic Details
Main Authors: Louise Lacalendola Tundisi, Diego de Freitas Coêlho, Alessandra Valéria de Sousa Faria, Adalberto Pessoa Junior, Elias Basile Tambourgi, Laura de Oliveira Nascimento, Edgar Silveira, Priscila Gava Mazzola
Format: Article
Language:English
Published: Universidade de São Paulo 2022-08-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Aqueous two-phases system
L-Asparaginase
Downstream processes
Bioprocessing
Fractional precipitation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100666&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100666&tlng=en

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