Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

ABSTRACT Streptococcus pneumoniae is a major human pathogen of global health concern and the rapid emergence of antibiotic resistance poses a serious public health problem worldwide. Fluoroquinolone resistance in S. pneumoniae is an intriguing case because the prevalence of fluoroquinolone resistanc...

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Bibliographic Details
Main Authors: Tina H. Dao, Haley Echlin, Abigail McKnight, Enolia S. Marr, Julia Junker, Qidong Jia, Randall Hayden, Tim van Opijnen, Ralph R. Isberg, Vaughn S. Cooper, Jason W. Rosch
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02828-23