Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Endotoxemia-activated tumor necrosis factor (TNFα)/nuclear factor kappa B (NFκB) signals result in acute on chronic inflammation-driven renal dysfunction in advanced cirrhosis. Systemic activation of peroxisome proliferator-activated receptor gamma (PPARγ) with pioglitazone can suppress inflammation...

Full description

Bibliographic Details
Main Authors: Szu-Yu Liu, Chia-Chang Huang, Shiang-Fen Huang, Tsai-Ling Liao, Nai-Rong Kuo, Ying-Ying Yang, Tzu-Hao Li, Chih-Wei Liu, Ming-Chih Hou, Han-Chieh Lin
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
endotoxemia
lipopolysaccharide
pioglitazone
cirrhosis
PPARγ
TNFα
Online Access:https://www.mdpi.com/2073-4409/10/11/3044

Internet

https://www.mdpi.com/2073-4409/10/11/3044

Similar Items