Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats

Endotoxemia-activated tumor necrosis factor (TNFα)/nuclear factor kappa B (NFκB) signals result in acute on chronic inflammation-driven renal dysfunction in advanced cirrhosis. Systemic activation of peroxisome proliferator-activated receptor gamma (PPARγ) with pioglitazone can suppress inflammation...

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Bibliographic Details
Main Authors:	Szu-Yu Liu, Chia-Chang Huang, Shiang-Fen Huang, Tsai-Ling Liao, Nai-Rong Kuo, Ying-Ying Yang, Tzu-Hao Li, Chih-Wei Liu, Ming-Chih Hou, Han-Chieh Lin
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Cells
Subjects:	endotoxemia lipopolysaccharide pioglitazone cirrhosis PPARγ TNFα
Online Access:	https://www.mdpi.com/2073-4409/10/11/3044

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