Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer

Summary: Pituitary adenoma-induced excess endocrine growth hormone (GH) secretion can lead to breast cancer development and metastasis. Herein, we used an acromegaly mouse model to investigate the role of excess endocrine GH on triple-negative breast cancer (TNBC) growth and metastasis. Additionally...

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Bibliographic Details
Main Authors: Chan Woo Kang, Ju Hun Oh, Eun Kyung Wang, Yaru Bao, Ye Bin Kim, Min-Ho Lee, Yang Jong Lee, Young Seok Jo, Cheol Ryong Ku, Eun Jig Lee
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224013622